Hepatitis C Testing
What to Expect When Getting Tested
All adults, pregnant women, and
people with risk fac
tors should
get tested for hepatitis C.
Most people who get infected with hepatitis C
virus (HCV) develop a chronic, or lifelong,
infection. Left untreated, chronic hepatitis C
can cause serious health problems, including
liver damage, cirrhosis, liver cancer, and even
death. People can live without symptoms or
feeling sick, so testing is the only way to know if
you have hepatitis C. Getting tested is important
to nd out if you are infected so you can get
lifesaving treatment that can cure hepatitis C.
Getting tested for hepatitis C
A blood test, called an HCV antibody test, is used to nd
out if someone has ever been infected with the hepatitis C
virus. The HCV antibody test, sometimes called the
anti-HCV test, looks for antibodies to the hepatitis C
virus in blood. Antibodies are chemicals released into
the bloodstream when someone gets infected.
Test results can take anywhere from a few days to a few
weeks to come back. Rapid anti-HCV tests are available
in some health clinics and the results of these tests are
available in 20 to 30 minutes.
What does a non-reactive HCV
antibody test result mean?
A non-reactive or negative antibody test means that
you are not currently infected with the hepatitis C virus.
However, if you think you might have been exposed to
hepatitis C in the last 6 months, you will need to be
tested again.
What does a reactive HCV antibody
test result mean?
A reactive or positive antibody test means you have been
infected with the hepatitis C virus at some point in time.
Once people have been infected, they will always have
antibodies in their blood. This is true if they have cleared the
virus, have been cured, or still have the virus in their blood.
A reactive antibody test does not necessarily mean that you
currently have hepatitis C and a follow-up test is needed.
What to do if the HCV antibody test
is reactive
If the antibody test is reactive or positive, you need an
additional test to see if you currently have hepatitis C.
This test is called a nucleic acid test (NAT) for HCV RNA.
Another name used for this test is a PCR test.
If the NAT for HCV RNA is:
Negative - you were infected with hepatitis C virus,
but the virus is no longer in your body because you
were cured or cleared the virus naturally.
Positive - you now have the virus in your blood.
If you have a reactive antibody test and a positive NAT
for HCV RNA, you will need to talk to a doctor about
treatment. Treatments are available that can cure most
people with hepatitis C in 8 to 12 weeks.
www.cdc.gov/hepatitis
April 2020