DRUGS OF ABUSE I A DEA Resource Guide: 2017 EDITION 75
Leaf of marijuana plant
• Heightened imagination leading to a subjective sense of
increased creativity
• Time distortions
• Illusions, delusions, and hallucinations are rare except
at high doses
• Impaired judgment, reduced coordination, and ataxia, which
can impede driving ability or lead to an increase in risk-
taking behavior
• Emotional lability, incongruity of affect, dysphoria, disor-
ganized thinking, inability to converse logically, agitation,
paranoia, confusion, restlessness, anxiety, drowsiness, and
panic attacks may occur, especially in inexperienced users or in
those who have taken a large dose
• Increased appetite and short-term memory impairment
are common
What is its effect on the body?
Short-term physical effects from marijuana use may include:
• Sedation, bloodshot eyes, increased heart rate, coughing
from lung irritation, increased appetite, and decreased
blood pressure
Marijuana smokers experience serious health problems such
as bronchitis, emphysema, and bronchial asthma. Extended
use may cause suppression of the immune system. Withdrawal
from chronic use of high doses of marijuana causes physical
signs including headache, shakiness, sweating, and stomach
pains and nausea.
Withdrawal symptoms also include behavioral signs such as:
• Restlessness, irritability, sleep difficulties, and de-
creased appetite
What are its overdose effects?
No deaths from overdose of marijuana have been reported.
Which drugs cause similar effects?
Hashish and hashish oil are drugs made from the cannabis plant
that are like marijuana, only stronger.
Hashish (hash) consists of the THC-rich resinous material of the
cannabis plant, which is collected, dried, and then compressed
into a variety of forms, such as balls, cakes, or cookie like sheets.
Pieces are then broken off, placed in pipes or mixed with tobacco
and placed in pipes or cigarettes, and smoked.
The main sources of hashish are the Middle East, North Africa,
Pakistan, and Afghanistan.
Hashish Oil (hash oil, liquid hash, cannabis oil) is produced by
extracting the cannabinoids from the plant material with a solvent.
The color and odor of the extract will vary, depending on the
solvent used. A drop or two of this liquid on a cigarette is equal
to a single marijuana joint. Like marijuana, hashish and hashish
oil are both Schedule I drugs.
What is its legal status in the United States?
Marijuana is a Schedule I substance under the Controlled
Substances Act, meaning that it has a high potential for abuse, no
currently accepted medical use in treatment in the United States,
and a lack of accepted safety for use under medical supervision.
Although some states within the United States have allowed the
use of marijuana for medicinal purpose, it is the U.S. Food and
Drug Administration that has the federal authority to approve
drugs for medicinal use in the U.S. To date, the FDA has not ap-
proved a marketing application for any marijuana product for any
clinical indication. Consistent therewith, the FDA and DEA have
concluded that marijuana has no federally approved medical
use for treatment in the U.S. and thus it remains as a Schedule I
controlled substance under federal law.
Marinol, a synthetic version of THC, the active ingredient
found in the marijuana plant, can be prescribed for the control
of nausea and vomiting caused by chemotherapeutic agents
used in the treatment of cancer and to stimulate appetite in
AIDS patients. Marinol is a Schedule III substance under the
Controlled Substances Act.